Haemophilus influenzae type b infections and its prevention by vaccines

Immunogenicity and Efficacy of Different Haemophilus influenzae type b Vaccines

Haemophilus influenzae, a major cause of meningitis in young children leading to death and other neurological sequelae. The disease leaves 15 to 35% of the survivors with permanent disabilities, such as, mental retardation or deafness. Despite the availability of new and more powerful antibiotics children with Hib meningitis still suffer from high mortality or morbidity. The emergence of multir...

Haemophilus influenzae type B conjugate vaccines.

In summary, all of the Hib conjugate vaccines are highly immunogenic and efficacious in children older than 12-15 months of age, and HbOC, PRP-OMPC, and PRP-T are highly immunogenic and demonstrated to be efficacious in infants as young as 2 months old. HbOC, PRP-OMPC, and PRP-T have been licensed in numerous countries for infants and are recommended for infant immunization. However, perhaps th...

immunogenicity and efficacy of different haemophilus influenzae type b vaccines

haemophilus influenzae, a major cause of meningitis in young children leading to death and other neurological sequelae. the disease leaves 15 to 35% of the survivors with permanent disabilities, such as, mental retardation or deafness. despite the availability of new and more powerful antibiotics children with hib meningitis still suffer from high mortality or morbidity. the emergence of multir...

Haemophilus influenzae type b polysaccharide vaccines.

Haemophilus influenzae type b infections in adults.

31 cases of invasive Haemophilus influenzae type b infections occurred in adults in Denmark during a period of 2 years and 5 months corresponding to an incidence of 0.3/100,000/year. Only 6 patients had no underlying condition. The incidence of H. influenzae type b infections in adults will probably rise in the future, because the increasing use of therapeutic measures affecting the immune syst...